Neurologist and stem cell biologist, director of the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA; previously spent many years at Stanford University.
Studies why stem cells in muscle and other tissues repair less well with age, and whether that process can be reversed.
Senior author of a well-known Nature study (2005) on parabiosis in mice: when the circulation of a young and an old mouse was joined, the old mouse’s muscle stem cells repaired better.
That work launched the search for ‘rejuvenating’ factors in blood — and also commercial young-plasma infusions, which the US FDA warned against in 2019.
Also described how resting stem cells ‘prime’ themselves for repair after injury, a mechanism that sheds light on tissue repair in ageing.
He also publishes reviews on what ‘rejuvenation’ means biologically and how to measure it reliably.
Takeaway: the rejuvenation results come from animal studies; paid ‘young blood’ treatments have no proven benefit in humans.