María Blasco is a Spanish molecular biologist. From 2011 to early 2025 she was director of the Spanish National Cancer Research Centre (CNIO) in Madrid.
Her research centres on telomeres, the protective ends of chromosomes, and the enzyme telomerase, and their role in ageing and cancer.
As a postdoc in Carol Greider’s lab she helped create the first mice lacking telomerase, showing what happens when telomeres shorten generation after generation.
Her team later showed that a telomerase gene therapy in adult and old mice extended healthy lifespan and lifespan without increasing cancer.
She is also exploring applications in diseases with very short telomeres, such as lung fibrosis, and wrote the book Morir joven, a los 140 (2016) with journalist Mónica G. Salomone.
For longevity, her work moved telomeres from a marker to a possible treatment target.
Takeaway: telomerase therapy does not yet exist for humans; be wary of supplements promising to lengthen your telomeres.