Engy › Who's who in longevity › Marco Demaria
At a glance
- Group leader at the European Research Institute for the Biology of Ageing (ERIBA) at UMCG and the University of Groningen.
- As a postdoc in Judith Campisi’s lab (Buck Institute, US) he showed in Developmental Cell in 2014 that senescent cells play a useful role in wound healing — so they are not only harmful.
- Studies how cells become senescent, which inflammatory signals they release and how to dampen those effects without losing their useful functions, for example during cancer treatment and in organ ageing.
- Part of the European SENESCENCE2030 network, which published a roadmap towards ‘precision senescence medicine’ in Nature Aging in 2026.
- Also publishes broad reviews, such as a 2026 piece in The EMBO Journal on sixty years of senescence research.
- Relevant because senolytics are often hyped; his work helps separate promising lab findings from what has actually been shown in humans.
Recent
- Study Cellular senescence: six decades of discovery and reinvention
- Study Metabolism licenses the senescence secretome
- Study A consensus roadmap from the SENESCENCE2030 network towards precision senescence medicine
- Study Misha Blagosklonny: a life of ideas
- Study Disruption of CDK4/6-RARα-NF-κB axis attenuates senescence-associated inflammation and improves function during aging and following chemotherapy